Extract executables by typing "tar xvf omcBPPS1.0.tar" A linux version of the program is in the omcbpps1.0/bin directory. The executable 'omcBPPS' was compiled under a RedHat 5.9 Linux operating system (kernelrelease 2.6.18-371.1.2.el5) running on an Intel Xeon x86_64 machine. Type ./omcBPPS for usage. The input multiple sequence alignment needs to be in cma format. The fa2cma program can be used to convert from fasta alignment format to cma. Example input alignments are provide. The omcBPPS program can be applied to these from the examples directory using the ./run_* scripts. Reference: Neuwald, A.F. 2014. A Bayesian sampler for optimization of protein domain hierarchies. Journal of Computational Biology 21(3):269-286 Extract executable by typing "tar xvf evalBPPS1.0.tar" A linux version of the program is in the evalbpps1.0/bin directory. The executable 'evalBPPS' was compiled under a RedHat 5.9 Linux operating system (kernelrelease 2.6.18-371.1.2.el5) running on an Intel Xeon x86_64 machine. Type ./evalBPPS for usage. The input files correspond to the output files created by the omcBPPS program. evalBPPS compares the results from different omcBPPS runs on the same input multiple sequence alignment. For details regarding the evalBPPS program, see the following reference. Reference: Neuwald, A.F. 2014. Evaluating, comparing and interpreting protein domain hierarchies. Journal of Computational Biology 21(4): 287-302. For further information contact: Andrew F. Neuwald Institute for Genome Sciences and Department of Biochemistry & Molecular Biology University of Maryland School of Medicine Baltimore, MD 21201 Tel: 410-706-6724; E-mail: aneuwald@som.umaryland.edu Home page: http://www.medschool.umaryland.edu/profiles/Neuwald-Andrew